Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We UseOxford University Press, 7 сент. 2006 г. - Всего страниц: 336 The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful. |
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Стр. 5
... isolated from a chicken. In 1909, a farmer from Long Island brought a Plymouth Rock hen to Peyton Rous at the Rockefeller Institute. The chicken had a large muscle tumor in her right breast, and the farmer wanted Rous to remove it. To ...
... isolated from a chicken. In 1909, a farmer from Long Island brought a Plymouth Rock hen to Peyton Rous at the Rockefeller Institute. The chicken had a large muscle tumor in her right breast, and the farmer wanted Rous to remove it. To ...
Стр. 6
... isolated a gene from a rat's brain tumor. Weinberg christened it the neugene to signify its origin from a neurological tumor and moved on to other fields. He did not clone the protein of the neu gene, a relatively easy experiment to do ...
... isolated a gene from a rat's brain tumor. Weinberg christened it the neugene to signify its origin from a neurological tumor and moved on to other fields. He did not clone the protein of the neu gene, a relatively easy experiment to do ...
Стр. 7
... isolated from rat sarcoma virus.6 They successfully created tumor cells by adding genetic flaws to normal human cells. Gradually, evidence began to amass that pointed to the possibility that cancer was triggered by oncogenes. An ...
... isolated from rat sarcoma virus.6 They successfully created tumor cells by adding genetic flaws to normal human cells. Gradually, evidence began to amass that pointed to the possibility that cancer was triggered by oncogenes. An ...
Стр. 13
... isolated from Madagascar periwinkle, which earned its name for its abundance on this African island. Its Latin name is Catharanthus roseus, which used to be called Vinca rosea. In 1958, during their pursuit of dia- betes drugs, R. L. ...
... isolated from Madagascar periwinkle, which earned its name for its abundance on this African island. Its Latin name is Catharanthus roseus, which used to be called Vinca rosea. In 1958, during their pursuit of dia- betes drugs, R. L. ...
Стр. 14
... isolated from the Pacific yew tree as part of the National Cancer Institute-United States Department of Agriculture (NCI-USDA) plant-screening program. The NCI is one of the many divisions of the National Institutes of Health (NIH) ...
... isolated from the Pacific yew tree as part of the National Cancer Institute-United States Department of Agriculture (NCI-USDA) plant-screening program. The NCI is one of the many divisions of the National Institutes of Health (NIH) ...
Содержание
3 | |
2 Drugs to Kill Germs | 43 |
From Nitroglycerin to Lipitor | 75 |
4 Sex and Drugs | 103 |
5 Drugs of the Mind | 129 |
6 Diabetes Drugs | 165 |
7 Anesthetics | 187 |
8 AntiInflammatory Drugs | 213 |
9 Reflections | 241 |
Chemical Structures | 245 |
Trademarks of the Drugs | 277 |
Bibliography | 281 |
Index | 295 |
Другие издания - Просмотреть все
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Ограниченный просмотр - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Ограниченный просмотр - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use Jie Jack Li Ограниченный просмотр - 2006 |
Часто встречающиеся слова и выражения
ACE inhibitors acid active agents alcohol anesthesia anesthetic antibacterial antibiotics antidepressants aphrodisiac approved aspirin Avastin Banting barbiturates became beta-blockers biological blood breast cancer Bristol-Myers Squibb calcium cancer drugs cause cells Chain chemical chemist chemistry chemotherapy chloroform chlorpromazine cholesterol clinical trials cocaine compounds cortisone depression developed diabetes discovered disease doses drug discovery EGFR enzyme estrogen ether extract Florey Gleevec guinea pigs haloperidol heart hormone human inhibit inhibitors initially injection insulin Iressa isolated kinase laboratory later leukemia leukotriene Lilly Lipitor lithium liver Macleod Marsilid medicine Merck metabolism mevastatin million molecule Morton nitroglycerin nitrous oxide Nobel Prize Novartis oral pancreas Parke-Davis patients penicillin Pfizer pharmaceutical Physiology production Prontosil prostaglandin protease protein Prozac receptor rheumatoid arthritis Roche scientists serotonin side effects Squibb statins streptomycin sulfanilamide Syntex synthesis tamoxifen Taxol tested therapy tion toxic trade name treating treatment tuberculosis tumors University Viagra virus Waksman